Microscopic Colitis Information - symptom, cause, picture, treatment of Microscopic Colitis

Microscopic Colitis Information

Microscopic colitis is an idiopathic condition in which patients have chronic watery diarrhea with normal-appearing mucosa at endoscopy. There appear to be two subtypes—lymphocytic colitis and collagenous colitis. In both, histologic evaluation of mucosal biopsies reveals chronic inflammation (lymphocytes, plasma cells) in the lamina propria and increased intraepithelial lymphocytes. Collagenous colitis is further characterized by the presence of a thickened band (> 10 m) of subepithelial collagen. Both forms occur more commonly in women, especially in the fifth to sixth decades. Symptoms tend to be chronic or recurrent but may remit in most patients after several years. Chronic NSAID therapy has been implicated as a causative factor in up to 50% of cases.

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